Mona Hammond came to England in 1959 and won a scholarship to the Royal Academy of Dramatic Art. Her first leading role was Lady Macbeth at the Roundhouse in 1970. She later starred in many plays by a new generation of black writers including Sweet Talk by Michael Abbensetts, 11 Josephine House by Alfred Fagon and several Mustapha Matura plays : As Time Goes By, Play Mas and Playboy of the West Indies.
In the 1970s Hammond appeared in several television dramas, landing the major role of Mrs Wolcott in Wolcott (1980-81), a 3-part ATV mini-series about a black detective based in East London. Her television career continued through roles in Black Silk (BBC, 1985), Playboy of the West Indies (BBC, 1985), When Love Dies (d. Horace Ove, 1990) and a five-year stint as Blossom Jackson in EastEnders (BBC, 1994-99).
Desmond's (Channel 4, 1990-4), Chef! (BBC, 1996) and Brothers and Sisters (BBC, 1998) showed off her comedy acting talents. Her latest roles include featured roles in high profile dramas Babyfather (BBC, 2001) and White Teeth (Channel 4, 2002).